FNA cytology of solitary fibrous tumors and the diagnostic value of STAT6 immunocytochemistry
نویسندگان
چکیده
منابع مشابه
Diagnostic value of a monoclonal anti-STAT6 antibody for solitary fibrous tumors: immunohistochemical analyses
Solitary fibrous tumors (SFTs) have been shown to harbor the characteristic NAB2-STAT6 gene fusion. Some recent studies have suggested that STAT6 is a useful marker for the diagnosis of SFTs. The aim of this study was to evaluate the diagnostic value of monoclonal anti-STAT6 in the distinction of SFTs from histologic mimics. The expression of STAT6 was evaluated in tissue microarrays and in who...
متن کاملThe clinicopathological significance of NAB2‐STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors
NAB2-STAT6 gene fusion drives STAT6 nuclear expression and is the pathognomonic hallmark of solitary fibrous tumors (SFTs). However, no study has systematically analyzed the clinicopathological features, STAT6 immunoexpression status, or the fusion variants of NAB2-STAT6 in intrathoracic SFTs. Fifty-two intrathoracic SFTs were retrieved to appraise histopathology, assess STAT6 immunoexpression,...
متن کاملHead and neck solitary fibrous tumors: diagnostic and therapeutic challenges.
OBJECTIVES/HYPOTHESIS Head and neck solitary fibrous tumors (SFTs) are quite rare, with <200 cases reported in the literature. The purpose of this study was to analyze the diagnostic and therapeutic challenges of this rare disease while reporting the largest head and neck case series. STUDY DESIGN Retrospective review. METHODS Between 1991 and 2011, 13 cases of head and neck SFTs from the p...
متن کاملSolitary fibrous tumor of the intrathoracicgoiter
Solitary Fibrous Tumors (SFTs) are rare primary pleural neoplasms which have recently been reported in extra-thoracic sites. In this report, solitary fibrous tumor arising in an intra-thoracic goiter with no evidence of cervical mass in a 74-year-old obese man who was found to have a large superior mediastinal mass with tracheal deviation on Chest X-Ray is presented.
متن کاملSolitary fibrous tumors of the pleura.
PURPOSE OF REVIEW Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm of the pleura. Although an increasing number of case series have been reported in recent years, so far clinical behavior is still unpredictable. The following article presents a detailed review of the recent larger series of SFTP with particular attention to the clinical presentation, pathologic characteristics and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Cytopathology
سال: 2017
ISSN: 1934-662X
DOI: 10.1002/cncy.21923